Identification of new DNA i-motif binding ligands through a fluorescent intercalator displacement assay† †Electronic supplementary information (ESI) available: Experimental, supporting fluorescence and UV-Vis data, Job plot, binding curves, CD spectra, melting temperatures and SPR data. See DOI: 10.1039/c7ob00710h

8-Styryl-substituted coralyne derivatives as DNA binding fluorescent probes† †Electronic supplementary information (ESI) available: Experimental procedures, additional spectroscopic data, 1H and 13C NMR spectra of 2 and 4a–f. See DOI: 10.1039/c6ra27684a Click here for additional data file.

Preferential targeting of i-motifs and G-quadruplexes by small molecules† †Electronic supplementary information (ESI) available: Experimental details, synthetic procedures, characterization data of compounds, 1H NMR and 13C NMR spectra, FRET melting, TO displacement, smFRET, lifetime data, CD spectra, western blot, dual luciferase, caspase assay. See DOI: 10.1039/c7sc02693e Click here for additional data file.

Department of Organic Chemistry, Indian A Jadavpur, Kolkata-700032, India. E-mail: oc Department of Physical Chemistry, Indian A Jadavpur, Kolkata-700032, India † Electronic supplementary information synthetic procedures, characterization d NMR spectra, FRET melting, TO displ spectra, western blot, dual luciferase, casp ‡ Present address: Department of Ch Education & Research, Bhopal, Bhopal-46...

The importance of loop length on the stability of i-motif structures† †Electronic supplementary information (ESI) available: Experimental details, UV melting curves at 295 nm, and CD spectra at pH 5 and 8. See DOI: 10.1039/c4cc07279k Click here for additional data file.

Experimental All chemicals and oligonucleotides were purchased from Sigma-Aldrich. Oligonucleotides were purified by reverse phase column by Sigma-Aldrich and characteristic mass spectroscopy data is provided in table S1. UV spectroscopy was carried out using an Agilent Cary 100 with a temperature controlled 6 x 6 cell changer. CD spectra were collected on beamline B23 at Diamond Light Source. ...

Identification of key structural features of the elusive Cu–Aβ complex that generates ROS in Alzheimer’s disease† †Electronic supplementary information (ESI) available: Fluorescence data, UV-vis curves, XANES and EPR data, EPR parameters table, 1H NMR data and a proposed mechanism of O2 reduction. See DOI: 10.1039/c7sc00809k Click here for additional data file.

Tandem trimer pyrrole–imidazole polyamide probes targeting 18 base pairs in human telomere sequences† †Electronic supplementary information (ESI) available: Materials and methods, sequences of ODN-1 to 5, mass spectra and analytical HPLC profiles of the compounds TH59, TT59, TAMRA TH59 and TAMRA TT59, the UV-visible absorption and fluorescence spectra of probes TAMRA TH59 and TAMRA TT59, SPR sensorgrams of TH59 and TT59, additional images of telomeres. See DOI: 10.1039/c4sc03755c Click here for additional data file.